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            Abstract Studies that concurrently investigate the functional benefits of group living in multiple populations of the same species are rare. Over a 3‐year period (2014–2016), we examined two ecologically contrasting populations to test multiple hypotheses for the adaptive significance of group living in the communally breeding rodentOctodon degus. We quantified the size of social units (number of adults, number of adult females), edible vegetation at burrow systems, and per capita offspring weaned (PCOW) in each population. Contrary to expectations, we did not observe population‐specific associations between group size and edible vegetation or PCOW nor universal benefits of group living. In one population, PCOW increased in mid‐sized groups with more edible vegetation. However, this trend was not consistent across years. Notably, we observed a complete reproductive failure in one population during the first year of study, one that was characterized by low rainfall and no detectable edible vegetation. This result is important because reproductive failure occurred regardless of group size, suggesting that communal living may not buffer degus against the harshest of environmental conditions. Examining how social organization shapes individual reproductive success under extreme variation in food availability is an important step towards understanding how populations will respond to a changing climate.more » « less
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            Mok, Jacob; Malpartida, Juan Carlos; O'Dell, Kimberly; Davis, Joshua; Gao, Cuilan; Manyam, Harish (, Open Heart)null (Ed.)Background Prior diagnosis of heart failure (HF) is associated with increased length of hospital stay (LOS) and mortality from COVID-19. Associations between substance use, venous thromboembolism (VTE) or peripheral arterial disease (PAD) and its effects on LOS or mortality in patients with HF hospitalised with COVID-19 remain unknown. Objective This study identified risk factors associated with poor in-hospital outcomes among patients with HF hospitalised with COVID-19. Methods Case–control study was conducted of patients with prior diagnosis of HF hospitalised with COVID-19 at an academic tertiary care centre from 1 January 2020 to 28 February 2021. Patients with HF hospitalised with COVID-19 with risk factors were compared with those without risk factors for clinical characteristics, LOS and mortality. Multivariate regression was conducted to identify multiple predictors of increased LOS and in-hospital mortality in patients with HF hospitalised with COVID-19. Results Total of 211 patients with HF were hospitalised with COVID-19. Women had longer LOS than men (9 days vs 7 days; p<0.001). Compared with patients without PAD or ischaemic stroke, patients with PAD or ischaemic stroke had longer LOS (7 days vs 9 days; p=0.012 and 7 days vs 11 days, p<0.001, respectively). Older patients (aged 65 and above) had increased in-hospital mortality compared with younger patients (adjusted OR: 1.04; 95% CI 1.00 to 1.07; p=0.036). Prior diagnosis of VTE increased mortality more than threefold in patients with HF hospitalised with COVID-19 (adjusted OR: 3.33; 95% CI 1.29 to 8.43; p=0.011). Conclusion Vascular diseases increase LOS and mortality in patients with HF hospitalised with COVID-19.more » « less
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